Thanks for the quick answers.
I am playing Galaxy Gigantic and Type Random.
Opponents are : Drengin,Yor,Altarians and Iridium
Everything else on custom settings because I am learning the game,I also didn´t build any ship.
First turns enabled manufacturing focus and then turned to research, now manufacturing slider is 80% militar and social 20%
I have all victory conditions enabled and 47% of influence victory, then 16% of conquest vic and 16% of technology vict.Could build several small ships but useless against Drengins.
Also using durantium,antimatter,prometion,thulium and approval relic.
I stopped the game because I believe am a few turns away from defeat and don`t want to begin a new one without a proper guide,this is my second game and in the previous one reached turn 160 before those Drengins destroyed my systems.Of course I could play without that faction enabled but there must be a way to overcome this.....
Most important question you didn't answer: what difficulty?
I'd recommend a smaller map with more AI to start out. They'll all be pissed at eachother for a very long time and give you a chance to get set up before they can actually do anything to you.
Don't ever put the military slider at 80%. It's the early game, you've got nothing but empty planets and you need to fill them with crap that you cannot afford to rush buy.
None of the strategic resources give you anything for holding them. Are you USING them for anything? Since you say you aren't designing your own ships, don't bother trying to get them as they are useless otherwise.
I think it's important to clear up a misconception you have: that drengin are strong. They are not. They are honestly one of the weak AI, along with the thalan. You're being taken in by their military power, when that's their shtick. Tons of good ships is their whole thing - you won't be beating them that way until you get very good at the game. Don't let your path to victory be dictated by AI: decide how you will win, and go do it. You might go for war, but you could also buy someone off to fight them, pump influence and flip everything, turtle and out-tech everybody, or take your ball and go home with all those ascension crystals.