Yea, first time I loaded the beta, it took forever. I got the "not responding" message, but decided to let it continue to try. A couple of minutes later it started up. I set up my first game and it crashed when I hit the "Manage" button on my home world.
I restarted the game and it came up normally and I was able to play. Something about the first game after patching seems to make it go nuts.