Obviously Windows 10 is currently in beta and thus unsupported, but in our tests DeskScapes is working just fine.
My build 10041 has developed an odd problem (compared to previous builds) whereby playing a mpeg1 stream .mpg file with DeskScapes 8.x will result in the Desktop animating correctly, but an 'ActiveMovie Window' pops up with the same video. In previous versions of Windows (Win7) this only happened when DeskScapes or appropriate video codecs weren't installed correctly, but on this particular build a fresh install of LAV Filters 0.64 and DeskScapes 8.21 has not solved the problem. So, just to let you know, not everything is peachy perfect right now. 
Could just as easily be this build and go away in the next, though.