Here what the game looks like in eyefinity on 1920 x 1080, have to disable the display group so it goes on one screen. Even in windowed clicking the buttons are off. Same problem for fallen enchantress. Heres the link. It's stretched badly.
Normaly it would just be the same on each screen. What would be best if all of the interface could be resized and moved around then it might be worth playing at the eyefinity resolution.