I've seen others post a few bug reports with bugs that go away upon save and reload, and I have found a few as well -- one ship will join another ship to form a fleet of 2, but I am unable to get more than 2 to merge to a larger fleet even when there is Logistical Slots room unless I save and reload; ship/fleet commands disable (the 'Command' greys out and Guard/Sentry controls are thus unavailable) after a save/reload.
I'm no expert by any means, but I think these seemingly disparate glitches are symptoms of a memory leak or other corruption of some sort because they can be resolved with a save/reload.