I played my first game last night and went back to the autosave today. That works just fine. I wanted to play long enough to try the basics: build a starbase, attack a ship and invade a planet. Everything worked. It was helpful to read the mini manual to see how to unlock ships.
I cannot comment much on the interface since anything that does not seem intuitive now will probably be fixed as time goes on although one thing that I noticed right away and is much appreciated is being able to move the map around with the keyboard arrow keys! I also liked the nebula storms as you zoomed out.
I did not see any odd behaviour nor did the game crash so for an alpha build it is pretty stable so far.
And contrary to the "not for fun" disclaimer it was entertaining! I cannot imagine putting too much time into it at this stage but I am anxiously waiting for the next build, the game does have me hooked so far!