I've been sticking with the classics this past week: 
Currently playing Birth of the Federation with the excellent Balance of Power mod installed.  Am also playing a Shimazu campaign in Shogun Total War (and holy crap, I forgot how tough their starting position can be!). 
Finally, I've started playing GalCiv 2 again (vanilla version) the last few days.  Currently have an Iconian campaign going in a Huge map, Normal difficulty, 9 opponents.  I've been fortunate to have the Torians, Altrarians, and Arceans as neighbors, as they all seem to be kindly disposed towards me (despite my complete lack of a military at the moment).  The Thalans are less happy about sharing a border with me, but I'm hoping I can still get them to warm up a bit.